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Dr. Peter Verdegem
Jul 14, 20192 min read
GPX-1
The GPX-1 gene produces a protein in your body called glutathione peroxidase. This protein is part of the antioxidant process in our...
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Dr. Peter Verdegem
Jul 14, 20192 min read
LCT
This week’s gene is a very well-known one: the gene that produces an enzyme called lactase, which is responsible in our body for...
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Dr. Peter Verdegem
Jul 7, 20192 min read
MTRR
MTRR is the part of the genome that produces an enzyme called methionine synthase. This enzyme’s role in our body is to use homocysteine...
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Dr. Peter Verdegem
Jul 6, 20192 min read
ADRB1
The beta-1 adrenergic receptor gene ADRB1 is listed in the blood pressure section of GenTest report. This gene regulates the effect that...
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Dr. Peter Verdegem
Jul 6, 20192 min read
LOC387715
This gene is in the section of the eye health, and determines in particular the risk for age-related macula degeneration. I have...
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Dr. Peter Verdegem
Jul 6, 20193 min read
FTO
This week’s gene has a nick name: the Fat Gene. Studies first related genetic variations in this gene to obesity and type-II diabetes in...
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Dr. Peter Verdegem
Jul 6, 20193 min read
COL1A1
The long name for this gene is Collagen Type I Alpha 1 Chain. It is a gene that codes a part of the collagen that is an essential part of...
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Dr. Peter Verdegem
Jul 6, 20193 min read
KCNJ11
This week I discuss a genetic variation that has another impact on the risk for type 2 diabetes, namely the KCNJ11 gene. Type 2 diabetes...
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Dr. Peter Verdegem
Jul 6, 20193 min read
ESR1
ESR1 is a gene that codes for one of the estrogen receptors. Estrogen is the primary female sex hormone. It is responsible for the...
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Dr. Peter Verdegem
Jul 6, 20192 min read
APOE
This week I again discuss two genetic variations at the same time. The reason being that they are part of the same gene, and that they...
17 views0 comments


Dr. Peter Verdegem
Jul 6, 20193 min read
CYP1B1
The cytochrome P450 (CYP) superfamily of enzymes catalyse one of the first steps in the metabolism of carcinogens such as polycyclic...
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Dr. Peter Verdegem
Jul 6, 20193 min read
APOB
This week, I discuss the ApoLipoprotein B gene, which is related to familiar hypercholesterolemia, or having a higher than normal...
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Dr. Peter Verdegem
Jul 6, 20193 min read
GNB3
This week’s gene, GNB3, or G-protein beta 3 subunit, is another example of a gene that has many influences on our health, and in a number...
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Dr. Peter Verdegem
Jul 6, 20193 min read
HTRA1
This week I discuss a gene that is close to my heart, as I have been awarded my PhD for research on the eye. My work was related to the...
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Dr. Peter Verdegem
Jul 6, 20193 min read
IL6
This week Gene of the Week discusses IL6, or interleukin 6. This gene codes for an important peptide that is part of the so-called acute...
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Dr. Peter Verdegem
Jul 6, 20193 min read
COMT
The COMT gene is listed under the detoxification section of GenTest. Yet, it is a prime example of a genetic variation that may result in...
21 views0 comments


Dr. Peter Verdegem
Jul 6, 20193 min read
GSTM and GSTT1
This week, I discuss two genetic variations at the same time, because they are so strongly related. Glutathion S-Transferase Mu 1 and...
56 views0 comments


Dr. Peter Verdegem
Jul 6, 20194 min read
MTHFR
Methylenetetrahydrofolate reductase in the long name for the enzyme that is produced by this gene. There has been a lot of attention for...
18 views0 comments


Dr. Peter Verdegem
Jul 6, 20193 min read
TNF-a
TNF-a stand for Tumor Necrosis Factor-alpha. It is a very important part of your biochemistry that plays a key role in the promotion of...
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Dr. Peter Verdegem
Jul 6, 20193 min read
SOD2
SOD2, or superoxide dismutase is a very important enzyme in our body. It operates mostly in the mitochondria, which are cell organelles...
17 views0 comments
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